Endocrine Abstracts

Introduction: The production of an oocyte competent of fertilisation and normal embryonic development is controlled by a series of highly organised signals and intracellular events which are known to be affected by physiological glucocorticoids. The actions of these adrenal steroids are modulated by 11β-hydroxysteroid dehydrogenase (11β-HSD) enzymes and we have recently reported that 11β-HSD activity in porcine oocytes increases 20-fold during meiotic maturation...